Some of the funniest bits of the Boosh are when Howard Moon, the straight-guy/deluded one, accepts surreal weirdness unquestioningly from Vince Noir (Noel Fielding) and joins in.
"Maybe she's trapped in a cabinet"
"People like her don't get trapped in cabinets"
"What about that programme, 'Trapped in Cabinets'?"
(Together, crimping)"Captain Cabinet, Trapped in cabinets, can he get out, will he get out...."
etc...
Like in Morecombe and Wise, it was the tension between Ernie Wise constantly trying to be "a serious performer", disapproving of his lunatic friend, and his giving into the temptation to join in that drove the comedy...
Without that, yes, you might just have a lunatic trying to be too weird for his own good.
@VCG, I will follow your advice and take the drugs an hour before the programme starts, but I will be out of the country on Thursday night, so I won't be able to watch it.